The symptoms of poisoning depend on the substance and the amount you take in.
Some poisonous substances, such as carbon monoxide, interfere with the blood's ability to carry oxygen. Others, such as bleach, burn and irritate the digestive system.
Parents and carers should be aware of sudden, unexplained illness in young children, particularly if they're drowsy or unconscious, because poisoning could be the cause.
Seek immediate medical advice if you think someone has swallowed a poisonous substance.
General symptoms
General symptoms of poisoning can include:
- feeling and being sick
- diarrhoea
- stomach pain
- drowsiness, dizziness or weakness
- high temperature
- chills (shivering)
- loss of appetite
- headache
- irritability
- difficulty swallowing (dysphagia)
- breathing difficulties
- producing more saliva than normal
- skin rash
- blue lips and skin (cyanosis)
- burns around the nose or mouth
- double vision or blurred vision
- mental confusion
- seizures (fits)
- loss of consciousness
- coma, in severe cases
Signs of a medicine or drug overdose
Medicine overdoses are the most common type of poisoning in the UK.
If someone takes too much of a medicine, they may experience symptoms specific to the medicine taken, as well as the more general symptoms listed above.
Some of the most common medicines or drugs involved in cases of poisoning are listed below.
Paracetamol
Paracetamol is a widely used over-the-counter painkiller.
Specific signs of paracetamol poisoning include:
- yellowing of the skin and the whites of the eyes (jaundice)
- loss of co-ordination
- low blood sugar (hypoglycaemia), which can cause symptoms including sweating, trembling and irritability
Aspirin
Aspirin is an anti-platelet medicine that thins the blood and reduces the risk of blood clots forming (arterial thrombosis).
Specific signs of aspirin poisoning include:
- sweating
- rapid breathing
- ringing in the ears (tinnitus)
- temporary hearing loss
Tricyclic antidepressants
Tricyclic antidepressants are used to treat clinical depression, as well as a number of other mental health conditions, such as panic disorder and obsessive compulsive disorder (OCD). Some types of tricyclic antidepressants can also be used to treat nerve pain.
Specific signs of poisoning with tricyclic antidepressants include:
- excitability
- dry mouth
- large pupils
- irregular or rapid heartbeat
- low blood pressure, which can cause symptoms including lightheadedness and fainting
Selective serotonin reuptake inhibitors (SSRIs)
SSRIs are a newer type of antidepressant that are also used to treat mental health conditions such as OCD and anxiety disorder.
Specific signs of SSRI poisoning include:
- feeling agitated
- tremor (shaking)
- uncontrolled movement of the eyes (nystagmus)
- severe muscle tension
Beta blockers
Beta blockers are used to treat a number of conditions that affect the heart or blood, such as high blood pressure (hypertension), angina and heart failure.
Specific signs of poisoning with beta blockers include:
- low blood pressure, which can cause symptoms such as lightheadedness and fainting
- a slow heartbeat (below 60 beats per minute)
Calcium-channel blockers
Calcium-channel blockers are used for the treatment of high blood pressure and angina.
Specific signs of calcium-channel blocker poisoning include:
- feeling agitated
- low blood pressure, which can cause symptoms such as lightheadedness and fainting
- chest pain
- a slow heartbeat (below 60 beats per minute)
Benzodiazepines
Benzodiazepines are a type of tranquiliser, often used on a short-term basis to treat anxiety and sleeping problems (insomnia).
Specific signs of poisoning with benzodiazepines include:
- co-ordination and speech difficulties
- uncontrolled movement of the eyes (nystagmus)
- shallow breathing
- drowsiness
Opioids
Opioids are a type of stronger painkiller used to treat moderate to severe pain. They include codeine and morphine, as well as the illegal drug heroin.
Specific signs of opioid poisoning include:
- small pupils
- shallow breathing
- drowsiness
Stimulant overdose
If you take too much of a stimulant-like drug, such as cocaine, amphetamine, crack or ecstasy, overdose signs can include:
- anxiety and paranoia
- restlessness or agitation
- hallucinations
- high temperature
- chest pain
- rapid breathing
- irregular or fast heartbeat
Cannabis overdose
If you smoke (or eat) too much cannabis, you may experience the following symptoms:
- paranoia
- hallucinations
- numbness in your arms and legs
Page last reviewed: 10 September 2021
Next review due: 10 September 2024