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Side effects of cyanocobalamin - Brand name: Orobalin

Most people do not have any side effects taking cyanocobalamin tablets.

Serious side effects of cyanocobalamin

As cyanocobalamin contains cobalt, it can cause sensitivity reactions in people who have an allergy to cobalt. Symptoms can start straight away or up to 3 days after having a dose.

Talk to your doctor or call 111 if you get an allergic skin reaction such as a rash or hives.

Serious allergic reaction

In rare cases cyanocobalamin can cause a serious allergic reaction (anaphylaxis).

Immediate action required: Call 999 now if:

  • your lips, mouth, throat or tongue suddenly become swollen
  • you're breathing very fast or struggling to breathe (you may become very wheezy or feel like you're choking or gasping for air)
  • your throat feels tight or you're struggling to swallow
  • your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
  • you suddenly become very confused, drowsy or dizzy
  • someone faints and cannot be woken up
  • a child is limp, floppy or not responding like they normally do (their head may fall to the side, backwards or forwards, or they may find it difficult to lift their head or focus on your face)

You or the person who's unwell may also have a rash that's swollen, raised, itchy, blistered or peeling.

These can be signs of a serious allergic reaction and may need immediate treatment in hospital.

Information:

Do not drive yourself to A&E.

The person you speak to at 999 will give you advice about what to do.

Other side effects

These are not all the side effects of cyanocobalamin. For a full list, see the leaflet inside your medicines packet.

Information:

You can report any suspected side effect using the Yellow Card safety scheme.

Visit Yellow Card for further information.

Page last reviewed: 26 July 2024
Next review due: 26 July 2027