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Side effects of cyclizine

Like all medicines, cyclizine can cause side effects, although not everyone gets them.

Common side effects

These common side effects of cyclizine happen in more than 1 in 100 people. They're usually mild and go away by themselves. There are things you can do to help cope with them:

Feeling drowsy

Do not drive, cycle or use tools or machinery if you're feeling this way. Do not drink alcohol, as it'll make you feel more tired. If this does not help, talk to your doctor. They may suggest a different anti-sickness medicine.

Blurred vision

Do not drive, cycle or use tools or machinery while this is happening. If it lasts for more than 2 days, speak to your doctor.

Dry mouth

Try chewing sugar-free gum or sucking sugar-free sweets.

Headaches

Rest and drink plenty of fluids. You can take an everyday painkiller like paracetamol or ibuprofen. Talk to your doctor if the headaches are severe or last longer than a week.

Constipation

Get more fibre into your diet, such as fresh fruit and vegetables and cereals. Try to drink several glasses of water or another non-alcoholic liquid each day. If you can, it may also help to increase your level of exercise.

Speak to a doctor or pharmacist if the advice on how to cope does not help and a side effect is still bothering you or does not go away.

Serious side effects

Serious side effects are rare and happen in less than 1 in 10,000 people.

Call your doctor or call 111 now if:

  • you get muscle stiffness or shaking, or unusual face or tongue movements
  • you get severe bleeding or bleeding that you cannot stop, such as cuts or nosebleeds that do not stop within 10 minutes
  • the whites of your eyes turn yellow, or your skin turns yellow although this may be less obvious on brown or black skin – these can be signs of liver problems

Serious allergic reaction

In rare cases, it's possible to have a serious allergic reaction (anaphylaxis) to cyclizine.

Immediate action required: Call 999 now if:

  • your lips, mouth, throat or tongue suddenly become swollen
  • you're breathing very fast or struggling to breathe (you may become very wheezy or feel like you're choking or gasping for air)
  • your throat feels tight or you're struggling to swallow
  • your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
  • you suddenly become very confused, drowsy or dizzy
  • someone faints and cannot be woken up
  • a child is limp, floppy or not responding like they normally do (their head may fall to the side, backwards or forwards, or they may find it difficult to lift their head or focus on your face)

You or the person who's unwell may also have a rash that's swollen, raised, itchy, blistered or peeling.

These can be signs of a serious allergic reaction and may need immediate treatment in hospital.

Information:

Do not drive yourself to A&E.

The person you speak to at 999 will give you advice about what to do.

Other side effects

These are not all the side effects of cyclizine. For a full list, see the leaflet inside your medicine packet.

Information:

Reporting side effects

You can report any suspected side effect using the Yellow Card safety scheme.

Visit the Yellow Card website for more information about reporting side effects.

Page last reviewed: 1 April 2022
Next review due: 1 April 2025