Cautions with other medicines
When taken at the same time, some medicines can affect the way esomeprazole works. Esomeprazole can also affect the way other medicines work.
Taking them together can make you more likely to have side effects or stop one of the medicines working as well.
Tell your doctor if you're taking any of these medicines before you start taking esomeprazole:
- heart medicines such as digoxin
- cilostazol, a medicine that treats peripheral arterial disease
- antifungal medicines such as itraconazole, ketoconazole, posaconazole or voriconazole
- methotrexate, a medicine that treats psoriasis and rheumatoid arthritis
- HIV medicines
- phenytoin, an epilepsy medicine
- rifampicin, an antibiotic
- clopidogrel or warfarin, medicines to prevent or treat blood clots
These are not all the medicines that may not mix well with esomeprazole. For a full list, see the leaflet inside your medicines packet.
Mixing esomeprazole with herbal remedies and supplements
Do not take St John's wort, the herbal remedy for depression, while you're taking esomeprazole. It may stop esomeprazole working as well as it should.
There's not enough information to say that other complementary medicines and herbal remedies are safe to take with esomeprazole. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.
Important: Medicine safety
Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.