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Pregnancy, breastfeeding and fertility while taking ibuprofen and codeine - Brand name: Nurofen Plus

Ibuprofen and codeine and pregnancy

While a short course of combined ibuprofen and codeine could be taken up to 20 weeks of pregnancy, other painkillers are likely to be more suitable.

Ibuprofen can affect your baby's circulation and amniotic fluid if you take it after 20 weeks, or for more than 2 to 3 days at a time.

Codeine can affect your baby, especially towards the end of pregnancy. Your baby may get used to having codeine and may have withdrawal symptoms when they're born. There is a slightly higher chance of your baby having breathing problems. These are usually temporary, but your baby may need to stay in hospital for extra monitoring.

Combined ibuprofen and codeine is not recommended during pregnancy. Other medicines are more suitable. Ask your doctor or pharmacist for advice.

Ibuprofen and codeine and breastfeeding

Do not take combined ibuprofen and codeine if you're breastfeeding. Talk to your doctor or pharmacist, as they will be able to recommend a more suitable painkiller.

Small amounts of the codeine may get into breast milk and can cause breathing problems in your baby and make them feel sleepy.

However, it's OK to take ibuprofen on its own while breastfeeding.

Ibuprofen and codeine and fertility

There's no evidence that taking combined ibuprofen and codeine for a maximum of 3 days will affect your fertility.

However, taking ibuprofen tablets in large doses or for a long time can affect ovulation. That might make it more difficult for you to get pregnant. You'll usually start ovulating normally again when you stop taking ibuprofen.

If you're worried about taking combined ibuprofen and codeine for longer than 3 days and how this may affect your fertility, talk to your doctor.

Non-urgent advice: Tell your doctor if you're:

  • trying to get pregnant
  • pregnant
  • breastfeeding
Information:

For more information about how ibuprofen and codeine can affect you and your baby during pregnancy, visit the Bumps (Best Use of Medicines in Pregnancy) website:

Page last reviewed: 1 April 2025
Next review due: 1 April 2028