Taking naproxen with other medicines and herbal supplements

Cautions with other medicines

There are some medicines that can affect the way naproxen works.

Tell your doctor if you're taking:

• other anti-inflammatory medicines, such as aspirin or ibuprofen
• medicines that help to prevent blood clots, such as warfarin or rivaroxaban
• steroids, such as prednisolone
• medicines that make you pee more (diuretics), such as furosemide
• medicines used to treat heart problems and high blood pressure
• antidepressants, such as citalopram
• medicine used to treat rheumatoid arthritis, such as methotrexate

Taking naproxen with other painkillers

Do not take naproxen with ibuprofen or other non-steroidal anti-inflammatory drugs (NSAIDs). But it's OK to take naproxen with paracetamol or co-codamol that you buy over the counter. This should just be for short periods of time.

If you often need to take extra painkillers with naproxen or for more than a few days, talk to your doctor. Sometimes, taking different painkillers together is a good way to relieve pain, but there may be other treatments you can try.

It's OK to take other painkillers with naproxen for longer if your doctor has given them to you on prescription and told you to take them together.

If you're unsure, talk to your doctor.

Mixing naproxen with herbal remedies and supplements

There's not enough information to say that complementary medicines and herbal remedies are safe to take with naproxen. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.