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Taking oxybutynin with other medicines and herbal supplements - Brand names: Aspire, Ditropan, Kentera

Cautions with other medicines

Oxybutynin may affect the way other medicines work, and other medicines may affect how oxybutynin works.

Tell your pharmacist or doctor if you're taking:

  • amantadine, a medicine used for Parkinson's disease or for infections
  • levodopa, used to treat Parkinson's disease
  • phenothiazines, clozapine, haloperidol or benperidol, medicines for mental health problems
  • donepezil, rivastigmine, galantamine or tacrine, medicines used for dementia
  • amitriptyline, imipramine or dosulepin (tricyclic antidepressants), medicines for depression
  • medicines used to make you feel sleepy (sedatives)
  • anti-sickness medicines like prochlorperazine
  • medicines for stomach and bowel problems like domperidone or metoclopramide
  • digoxin, quinidine or disopyramide, medicines used to treat heart problems
  • dipyridamole, used to treat blood problems
  • chlorphenamine or diphenhydramine, medicines used to treat allergies
  • any medicines used to treat irritable bowel syndrome, asthma, incontinence, motion sickness or movement disorders related to Parkinson's disease, that work in a similar way to oxybutynin
  • erythromycin or other macrolide antibiotics used to treat bacterial infections

Taking oxybutynin with painkillers

It's safe to take oxybutynin with everyday painkillers like paracetamol.

Mixing oxybutynin with herbal remedies and supplements

Some herbal remedies can make you feel sleepy, cause a dry mouth, or make it difficult to pee. Their effect is similar to oxybutynin. This can increase your risk of getting side effects or make your side effects worse.

There's not enough information to say that other complementary medicines and herbal remedies are safe to take with oxybutynin. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.

Important: Medicine safety

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.

Page last reviewed: 16 August 2024
Next review due: 16 August 2027