Cautions with other medicines
Some medicines and oxycodone can affect each other and increase the chance of getting side effects.
Tell your doctor before taking oxycodone if you are taking any medicines:
- to help you sleep
- for depression or a mental health condition – some types cannot be taken with oxycodone
- for high blood pressure (hypertension)
- to help stop you feeling or being sick (vomiting), such as domperidone, metoclopramide or aprepitant
- to treat symptoms of an allergy such as antihistamines
- to reduce tension or anxiety
- for an infection
- to control seizures or fits due to epilepsy
Taking oxycodone with other painkillers
It's safe to take oxycodone with paracetamol, ibuprofen or aspirin (do not give aspirin to children under 16 years of age).
Do not take oxycodone with painkillers that contain codeine. You'll be more likely to get side effects. These include:
- co-codamol (codeine and paracetamol)
- Nurofen Plus (codeine and ibuprofen)
- co-codaprin (codeine and aspirin)
- Solpadeine (codeine, paracetamol, ibuprofen and caffeine)
Mixing oxycodone with herbal remedies and supplements
There's not enough information to say whether complementary medicines, herbal remedies and supplements are safe to take with oxycodone. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.
Important: Medicine safety
Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.