Pregnancy, breastfeeding and fertility while taking sitagliptin

Sitagliptin and pregnancy

Sitagliptin is not recommended in pregnancy as there is little information about whether it may affect a developing baby.

If you are pregnant or thinking of getting pregnant, talk to your doctor as they will need to review your treatment. They will be able to suggest a different medicine that is safer for you to take in pregnancy.

Sitagliptin and breastfeeding

Sitagliptin is not usually recommended while you're breastfeeding. We do not know how much of it passes into breast milk, but it is likely to be a fairly small amount.

If you are breastfeeding, or planning to breastfeed, talk to your doctor about what's best for you and your baby. They will need to review your treatment and may be able to suggest a different medicine for you, particularly if you're breastfeeding a newborn or premature baby.

If your doctor says it's OK to keep breastfeeding, contact your health visitor, midwife, pharmacist or doctor as soon as possible if:

• your baby is not feeding as well as usual
• your baby seems unusually sleepy or drowsy
• your baby seems unusually restless or irritable
• your baby is paler, or more sweaty, than usual
• your baby seems hungrier than usual
• your baby is peeing more
• you have any other concerns about your baby

Sitagliptin and fertility

There's no evidence to suggest that taking sitagliptin reduces fertility in either men or women.

Speak to a pharmacist or your doctor if you're trying to get pregnant. They may want to review your treatment.

For more information about how diabetes medicines can affect you and your baby during pregnancy, visit the Best Use of Medicines in Pregnancy (BUMPS) website.