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Who can and cannot take sodium valproate - Brand names: Dyzantil, Epilim, Episenta, Epival

Who can take sodium valproate

Most adults can take sodium valproate to treat epilepsy or bipolar disorder or help prevent migraine.

Most children can take sodium valproate to treat epilepsy.

Who may not be able to take sodium valproate

Girls and women who need to take sodium valproate must be enrolled on Prevent, the valproate pregnancy prevention programme. Speak to your doctor about this.

Sodium valproate may affect fertility in men. There may also be a small chance of learning or behavioural problems in the baby if you are taking sodium valproate and your partner becomes pregnant. For these reasons, doctors may recommend different treatments for men who could possibly have children, or in those planning to try for a baby.

To make sure sodium valproate is safe for you, tell your doctor if you:

  • have ever had an allergic reaction to sodium valproate or any other medicine
  • have liver problems
  • have a rare metabolic or genetic condition such as porphyria, urea cycle disorder, mitochondrial disorder or primary carnitine deficiency

Find out more about Prevent, the valproate pregnancy prevention programme, on the Electronic Medicines Compendium website (PDF only, 318KB).

Page last reviewed: 11 March 2025
Next review due: 11 March 2028