Taking ticagrelor with other medicines and herbal supplements - Brand name: Brilique

Cautions with other medicines

There are some medicines that may affect how ticagrelor works.

Tell your doctor if you're taking any other medicines, including:

• other medicines to prevent blood clots, such as low-dose aspirin, warfarin, rivaroxaban, apixaban, edoxaban, dabigatran, dipyridamole, clopidogrel or prasugrel
• non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen
• antidepressants called selective serotonin reuptake inhibitors (SSRIs), such as citalopram
• some antibiotics like clarithromycin and rifampicin
• medicines for epilepsy, such as phenytoin and carbamazepine
• statins, such as rosuvastatin or simvastatin, used to lower cholesterol
• digoxin, for heart problems
• medicines to treat HIV, such as atazanavir, darunavir or ritonavir
• ciclosporin
• morphine
• antifungal medicines such as itraconazole and voriconazole

These are not all the medicines that may cause problems if you take them with ticagrelor. For a full list, see the leaflet inside your medicine packet.

Taking ticagrelor with everyday painkillers

Your doctor may prescribe low-dose aspirin (75mg tablets) to take together with ticagrelor.

Do not take aspirin for pain relief (300mg tablets) or ibuprofen while you're taking ticagrelor, unless a doctor has said it's OK. They increase the chance of bleeding.

You can take paracetamol together with ticagrelor.

Mixing ticagrelor with herbal remedies and supplements

There might be a problem with taking some herbal remedies and supplements with ticagrelor, especially ones that can affect your blood (for example, ginkgo).

St John's wort (used for depression) can reduce the levels of ticagrelor in your blood. This may stop ticagrelor from working properly and increase your chances of getting a blood clot.

There's not enough information to say that other complementary medicines and herbal remedies are safe to take with ticagrelor. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.