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Who can and cannot take valproic acid - Brand names: Belvo, Depakote, Convulex, Syonell

Who can take valproic acid

Most adults can take valproic acid to treat bipolar disorder or epilepsy or help prevent migraine.

Most children aged 1 month or older can take valproic acid to treat epilepsy.

Who may not be able to take valproic acid

Girls and women who need to take valproic acid must be enrolled on Prevent, the valproate pregnancy prevention programme.

Valproic acid may affect fertility in men. There may also be a small chance of learning or behavioural problems in the baby if you are taking valproic acid and your partner becomes pregnant. For these reasons, doctors may recommend different treatments for men who could possibly have children, or in those planning to try for a baby.

To make sure valproic acid is safe for you, tell your doctor if you:

  • have ever had an allergic reaction to valproic acid or any other medicine
  • have liver problems
  • have a rare metabolic or genetic condition such as porphyria, urea cycle disorder, mitochondrial disorder or primary carnitine deficiency

Find out more about Prevent, the valproate pregnancy prevention programme, on the Electronic Medicines Compendium website (PDF only, 318KB).

Page last reviewed: 11 March 2025
Next review due: 11 March 2028