Taking zopiclone with other medicines and herbal supplements

Cautions with other medicines

Some medicines and zopiclone can affect each other and increase the chances of you having side effects.

Certain medicines may increase the drowsy (sedating) effects of zopiclone.

Speak to your doctor or pharmacist before starting to take zopiclone if you take any of these medicines:

• medicines to treat schizophrenia or bipolar disorder
• medicines to treat depression
• medicines for epilepsy
• medicines to calm or reduce anxiety, or for sleep problems
• medicines for hay fever, rashes or other allergies that can make you sleepy (sedating antihistamines, such as chlorphenamine or promethazine)
• strong painkillers such as codeine, methadone, morphine, oxycodone, pethidine or tramadol
• erythromycin or clarithromycin, antibiotics used to treat infections
• medicines used to treat fungal infections, such as ketoconazole or itraconazole
• ritonavir, a medicine used to treat HIV infections

Mixing zopiclone with herbal remedies and supplements

Do not take any herbal remedies that make you feel sleepy while taking zopiclone.

They can increase the drowsy (sedating) effects of your medicine.